2003 Genomics:GTL-Related U.S. Department of Energy Small Business Innovation Research (SBIR) Projects
Three winners of 2003 SBIR Phase II awards may help to speed scientific discovery in the Genomics:GTL Program
Model-Driven Strain Design for Pseudomonas fluorescens
Genomatica, Inc.
5405 Morehouse Drive, Suite 210
San Diego, CA 92121-4722A computational technology will be developed to assemble a metabolic model based on genomic, biochemical, and physiological information that will predict cellular functions of organisms under changing physiological and genetic conditions. These predictive capabilities will enable the model to be useful in guiding future experimental research and process improvements.
Single-Cell Genomics of Hyperthermophiles
Lucigen Corporation
2120 W. Greenview Drive
Middleton, WI 53562-2547This project will sequence the genome of a single microbial cell, resulting in a 500-fold increase in the genetic information known about bacteria. Such knowledge will enable advances in medicine and biotechnology, as well as economic and environmental advances for industrial processing and increased understanding of microbes in the environment.
DNA Amplification of the Whole Genome from a Single Cell
A method will be developed to accurately produce millions of DNA copies
Molecular Staging Incorporated
300 George Street, 7th Floor
New Haven, CT 06511-6652
starting from a single bacterial cell, making it possible to sequence the genome of thousands of new bacterial species and accelerate research into microbiology, infectious diseases, and biological warfare.
For More on SBIR
- General SBIR information see http://sbir.er.doe.gov/sbir (or email: sbir-sttr@science.doe.gov; phone: 301/903-1414)
- GTL science and technology issues (email: Marvin.Stodolsky@science.doe.gov or phone 301/903-4475)
