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Genomic Science Program

Systems Biology for Energy and the Environment

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Genomic Science Program

Funding Announcements

Genomics-Enabled Plant Biology for Determination of Gene Function

The DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in receiving applications for research within the Biological Systems Science Division’s (BSSD) Genomic Science Program (GSP) (http://genomicscience.energy.gov) mission-space. This FOA solicits applications for: a) understanding of regulatory elements that control plant gene expression; b) approaches to understand the biological mechanisms that lead to differential gene expression of different members of gene families; and c) dissection of multigene traits and understanding their component parts.

  • Funding announcement: DE-FOA-0002601
  • Submission Deadline for Pre-applications: January 14, 2022 at 5:00 PM Eastern Time. A pre-application is required.
  • Pre-application Response Date: January 28, 2022 at 5:00 PM Eastern Time
  • Submission Deadline for Applications:  March 25, 2022 at 11:59 PM Eastern Time
  • Please see the announcement for additional details and eligibility requirements.

Systems Biology Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment

The U.S. Department of Energy (DOE), Office of Science (SC) announces the release of DE-FOA-0002602, a plan to provide up to $36 million for basic research into microbial processes and community interactions in natural systems. The research will elucidate fundamental principles to advance our understanding of regulatory, metabolic, and signaling networks among microbes, microbe-plant interactions, the capture and storage of carbon in soils, and the conversion of nutrients and other elements in a changing world.

Applications will be open to universities, industry, and nonprofit research institutions as the lead institution, with collaborators at the DOE national laboratories and other Federal agencies. Total planned funding is $36 million over three years, with outyear funding contingent on congressional appropriations.

  • Funding announcement: DE-FOA-0002602
  • Submission Deadline for Pre-applications: January 14, 2022 at 5:00 PM Eastern Time. A pre-application is required.
  • Deadline for ApplicationsNot Applicable. This Funding Opportunity Announcement (FOA) will remain open until September 30, 2022 or until replaced by a successor FOA. Applications may be submitted any time during that period.
  • Please see the announcement for additional details and eligibility requirements.

Biosystems Design to Enable Safe Production of Next-Generation Biofuels, Bioproducts, and Biomaterials

The U.S. Department of Energy (DOE), Office of Science (SC) announces the release of DE-FOA-0002600, a plan to provide up to $110 million for basic research and technology development to design and engineer plants and microbes for the production of advanced biofuels, bioproducts, and biomaterials. The research will elucidate fundamental biological processes to enable genome-scale redesign and editing to develop more productive and resilient crops and novel microbial strains that can efficiently produce valuable chemicals and materials that will advance a sustainable and secure bioeconomy.

Applications will be open to universities, industry, and nonprofit research institutions as the lead institution, allowing collaborations with DOE/NNSA National Laboratories and other Federal Agencies. Total planned funding is $110 million over five years, with outyear funding contingent on Congressional appropriations.

  • Funding announcement: DE-FOA-0002600
  • Deadline for Pre-applications (required): January 26, 2022 at 5:00 pm Eastern Time.
  • Pre-Application Response Date:  February 9, 2022 
  • Deadline for Applications: April 6, 2022 at 11:59 pm Eastern Time
  • Please see the announcement for additional details and eligibility requirements.

 

SBIR/STTR Call for Climate, Energy and Scientific R&D

The U.S. Department of Energy (DOE), Office of Science (SC) announces the release of DE-FOA-0002555, a plan to provide $54 million for small businesses pursuing climate and energy research and development (R&D) projects as well the development of advanced scientific instrumentation through a funding opportunity announcement (FOA). Areas of interest include renewable energy, carbon management, fusion and nuclear energy, advanced grid technologies, and cybersecurity

  • Funding announcement: DE-FOA-0002555
  • Post Date: Monday, December 13, 2021
  • Close Date: Tuesday, February 15, 2022
  • Submission Deadline for Letters of Intent: January 3, 2022, at 5:00 PM Eastern Time
  • Submission Deadline for Applications: February 15, 2022, at 11:59 PM Eastern Time
  • Please see the announcement for additional details and eligibility requirements.

 

Early Career Research Program

The U.S. Department of Energy (DOE), Office of Science (SC) announces the release of the FY-2022 Early Career Research Program (ECRP) Funding Opportunity: DE-FOA-0002563. This opportunity includes the following BER Biological System Science research topic:

    Systems Biology and Biosystems Design of Bioenergy-Relevant Microbes to Enable Production of Next-Generation Biofuels, Bioproducts, and Biomaterials. Applications are requested for systems biology research to advance the development of emerging eukaryote or prokaryote model microorganisms and/or microbial communities relevant for the production of biofuels, bioproducts, and/or biomaterials by converting lignocellulosic biomass, upcycling synthetic (petroleum-derived) polymers, or as a byproduct of photosynthesis. Applications that propose multi-omics approaches coupled with genome-wide design and editing technology development, in vivo or cell-free engineering, advanced predictive modeling, and high-throughput screening to understand and re-design biological systems with novel functional capabilities and biosynthetic potential are encouraged. Proposed studies could include, but are not limited to: i) elucidation and/or engineering of relevant regulatory and metabolic networks, metabolic pathways, and/or signal processing related to bioproduct synthesis by microbes or multispecies consortia; ii) development of synthetic biology tools to facilitate the study and manipulation of emerging microbial model systems; iii) understanding and modification of phenotypes involved in the deconstruction and conversion of plant cell walls or synthetic, petroleum-derived polymers, the tolerance to stresses induced by altered biosynthetic pathways or culture conditions, and/or the synthesis of biofuels, bioproduct, and material precursors; and iv) engineering microorganisms for the production of biominerals, inorganic-organic composites, and composites of inorganic materials and living cells (living materials), with wholly new properties not found in nature.

  • More information on the SC Early Career Research Program: https://www.energy.gov/science/listings/early-career-program.
  • Deadline for Pre-applications (required): October 21, 2021; 5 pm eastern time
  • Deadline for Applications: January 20, 2022; 11:59 pm eastern time
  • Please see the announcement for additional details and eligibility requirements.

Office of Science Graduate Student Research (SCGSR) Program 2021 Solicitation 1

The DOE Office of Science is pleased to announce that the SCGSR program is now accepting applications for the 2021 Solicitation 1. Applications are due Wednesday, May 5, 2021, at 5:00 p.m. Eastern Time. Detailed information about the program, including eligibility requirements and access to the online application system, can be found at: https://science.osti.gov/wdts/scgsr/.

The SCGSR program supports supplemental awards to outstanding U.S. graduate students to conduct part of their graduate thesis research at a DOE national laboratory/facility in collaboration with a DOE laboratory scientist for a period of 3 to 12 consecutive months—with the goal of preparing graduate students for scientific and technical careers critically important to the DOE Office of Science mission.

For any questions, please contact the SCGSR Program Manager, Dr. Ping Ge, at sc.scgsr@science.doe.gov.

 

DE-FOA-0002448 – Systems Biology of Bioenergy-Relevant Microbes to Enable Production of Next-Generation Biofuels and Bioproducts

The U.S. Department of Energy (DOE) announces a plan to provide up to $9 million for research on re-engineering microbes both for the production of advanced biofuels and other bioproducts and for the upcycling of polymers to reduce the environmental impact of discarded plastics. An aim of the biofuels research is to develop methods to cost-effectively convert plant biomass directly into advanced, energy-dense transportation fuels such as gasoline, diesel, and aviation fuel. The goal of the polymer upcycling effort, meanwhile, is to develop microbial approaches to converting discarded plastics into fuels, industrial chemicals, and other high-value products as a way of ultimately reducing the environmental impact of plastic waste. Research is expected to make use of a range of sophisticated genomics and other “omics” (e.g., transcriptomics, metabolomics) techniques as well as tools of computation biology.

Applications will be open to universities, industry, and nonprofits as the lead institution, with potential collaborators at the DOE national laboratories and other federal agencies. Funding is to be awarded competitively, based on peer review, and is expected to be in the form of three-year grants beginning in the current fiscal year. Total planned funding is up to $9 million over three years, contingent on congressional appropriations.

BER Imaging Research: DE-FOA-0002393 BER Bioimaging Research to Develop Imaging Instrumentation and Approaches

The Bioimaging Science program within DOE’s Office of Biological and Environmental Research (BER) supports research to create a versatile toolbox for imaging biological processes occurring within and among cells in living plants and microorganisms. These enabling capabilities seek to advance understanding that underpins DOE energy and environmental missions. Applications are requested for fundamental research enabling new bioimaging instrumentation capabilities to study plant and microbial systems in areas such as bioenergy research or other disciplines that BER supports.

Early Career Research Program: DE-FOA-0002421 Systems Biology Research to Advance Sustainable Bioenergy Crop Development

Applications are requested for systems biology-driven, basic research on the fundamental principles of sustainable bioenergy feedstocks in relationship to their ecosystem context. Proposed projects should be hypothesis-driven and focus on understanding feedstock productivity and the effects of nutrient availability and abiotic stresses (e.g., drought, heat, salt, light, etc.). A deep understanding of these processes and their integration into predictive modeling frameworks will enable the potential development of bioenergy crops that require less agronomic inputs, are tolerant to climatic and environmental stressors, and are resilient and/or adaptable to changing conditions. Species of interest include, but are not limited to, candidate bioenergy crops such as sorghum, energy cane, Miscanthus, switchgrass, Populus, etc., as well as non-food oilseed crops such as Camelina. Field research is encouraged as well as simplified laboratory environments as long as they result in knowledge that can be extrapolated to field settings. [More]

 


Closed Solicitations

 

Office of Science Graduate Student Research (SCGSR) Program 2020 Solicitation 1


The DOE Office of Science is pleased to announce that the SCGSR program is now accepting applications for the 2020 Solicitation 1.Applications are due 5:00 pm Eastern Time on Wednesday, May 6, 2020. Detailed information about the program, including eligibility requirements and access to the online application system, can be found at: https://science.osti.gov/wdts/scgsr/.

The SCGSR program supports supplemental awards to outstanding U.S. graduate students to conduct part of their graduate thesis research at a DOE national laboratory/facility in collaboration with a DOE laboratory scientist for a period of 3 to 12 consecutive months—with the goal of preparing graduate students for scientific and technical careers critically important to the DOE Office of Science mission.

For any questions, please contact the SCGSR Program Manager, Dr. Ping Ge, at sc.scgsr@science.doe.gov.

DE-FOA-0002214 - Systems Biology Research To Advance Sustainable Bioenergy Crop Development

  • Genomics-Enabled Plant Biology for Determination of Gene Function DE-FOA-0002601 [12/16/21]
  • Systems Biology-Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment DE-FOA-0002602 [12/15/21]
  • Biosystems Design to Enable Safe Production of Next-Generation Biofuels, Bioproducts, and Biomaterials DE-FOA-0002600 [12/13/21]
  • SBIR/STTR Funding Call for Climate, Energy and Scientific R&D DE-FOA-0002555 [12/13/21]
  • Quantum-Enabled Bioimaging and Sensing Approaches for Bioenergy DE-FOA-0002603 [11/15/21]
  • NAS Report: Quantum Science Concepts in Enhancing Sensing and Imaging Technologies: Applications for Biology. More »
  • JBEI's Jay Keasling named Office of Science Distinguished Scientist Fellow. More »
  • DOE BER Early Career Research Funding Opportunity Preapplications due Oct. 21. More »
  • Systems Biology of Bioenergy-Relevant Microbes Projects Awarded. [7/21] More »
  • BER Bioimaging Science Program announces new awards. [7/21] More »
  • DOE BER Request for Information – Responses due by 10- 31-21. More »
  • DOE BER Awards $45.5 Million [6/21] More »
  • More News and Announcements »

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